The Obese-Asthma Phenotype

Medical

Articles
September 2015

The Obese-Asthma Phenotype

In Brief

Obesity (body mass index > 30), already a known risk factor for hypertension, Type 2 diabetes, atherosclerosis and some forms of cancer, now presents with significant evidence as a major risk factor for asthma.

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Obesity – a well-recognized risk factor for diabetes, coronary artery disease, as well a few cancers – is also an important risk factor for asthma. It can present itself as a distinct asthma phenotype. Obese-asthmatics are likely to present with additional morbidity costs in terms of increased health care utilization, significant loss of working days and an overall poorer quality of life. This article discusses this phenotype, and explains the pathophysiological mechanism and impact of this on morbidity, disability and health care utilization in obese-asthmatic individuals.

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